Manchester United striker Rasmus Hojlund was subbed off in the second-half of their Premier League clash against Luton Town after clutching his hamstring.
The 20-year-old Danish international, who has been a first-team regular since his £72 million arrival this summer, went down in the 76th minute of Saturday's game.
After a conversation with Erik ten Hag and medical staff, he was replaced by Anthony Martial before heading straight down the Old Trafford tunnel.
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If serious, it will be a bitter blow to United, who are currently lacking depth in forward areas.
Hojlund, who is yet to score in the Premier League this season, has netted five Champions League goals for the Reds, including a brace in Saturday's 4-3 defeat to Copenhagen.
As you can imagine, United fans were understandably concerned when Hojlund was substituted with what appeared to be a muscle injury.
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One said: "I hope it's nothing serious. We have important matches in the Champions League. This is really a crucial time," while another commented: "If Hojlund’s out, it shouldn’t be Martial coming in at #9 - give some U23 kid a chance for once."
A third wrote: "This is on ETH. He should have been off earlier when he was clearly struggling."
A fourth added: "Hojlund injury? Is it muscular? Come on man we have to start looking at our rehabilitation methods and training."
United are already without a host of first-team regulars, including Lisandro Martinez, Luke Shaw and Jonny Evans, who has been ruled out for the "next few weeks" after suffering a thigh strain against Copenhagen.
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Back in October, the club launched an internal investigation into the excessive number of injuries suffered in the early stages of the campaign.
At the time, Hojlund, Sofyan Amrabat, Mason Mount and Sergio Reguilon, amongst others, were sidelined through injury.
And according to the Daily Mail, United officials were ‘actively’ inquiring to see whether there are any patterns in a bid to help solve the ongoing fitness problems.
Muscular problems were noted as a type of injury they wanted to eliminate.
Topics: Erik Ten Hag, Manchester United, Premier League, Rasmus Hojlund, Fan Reactions