Liverpool fans are amazed VAR didn't look at Southampton defender Lyanco bringing down Diogo Jota moments before the Saints opened the scoring.
Jurgen Klopp's side started the evening four points behind Manchester City and know a loss would give their rivals the title.
Nathan Redmond gave Southampton an early lead with a long-range effort that deflected in off James Milner, but many believe it shouldn't have stood.
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Seconds before Redmond scored, Lyanco went for a 50/50 with Jota and looked to take his man as well as the ball.
Referee Martin Atkinson let the game go on and VAR didn't think the challenge was worth viewing again.
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The Reds would equalise through Takumi Minamino not long after, but they know a draw isn't the best result.
Fans have reacted to the challenge and they think the standard of officiating was incredibly poor.
One commented: "I thought VAR was brought in to sort these things out ffs."
Another said: "More incompetence that could cost us, I'm tired."
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A third put: "That's utterly wild wow."
While someone tweeted: "People have the cheek to call us LiVARpool as well."
Liverpool won the FA Cup on Saturday after overcoming Chelsea 6-5 on penalties after an absorbing 120 minutes of action.
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Mohamed Salah and Virgil van Dijk went off with injuries in that game and miss out tonight.
All in all, Klopp has made nine changes to his team and only Alisson and Ibrahima Konate have kept their place.
Liverpool will end this season having played every game possible and Klopp believes it's important to manage his players' fitness.
"I had different things to consider, with the results Southampton have had against other top-six teams we need 100% desire, we need to be ready for a proper fight," the German told Sky Sports in his pre-match interview.
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"We have to be careful about who can go after 120 minutes again, who is physically in the situation and who is mentally in the situation because obviously the season is intense for the boys.
"After the game against Chelsea, celebrations, then being really happy, then we settled, then ah - Southampton.
"In the moment when I did the line-up I got really excited about it. Now we are here with a very positive feeling, we want to go for it. We know it's difficult but we have a team who will try absolutely everything to cause Southampton problems."
Topics: Liverpool, Premier League, Southampton