Paul Pogba appeared to make a gesture towards Manchester United fans at Old Trafford after being booed during Saturday’s unconvincing win over Norwich.
A hat-trick from Cristiano Ronaldo dragged United to a 3-2 victory over the Premier League's bottom side.
United fans protested against their club’s owners before kick-off and the atmosphere soured further after the Red Devils threw away a two-goal lead during the match.
Chants of “you’re not fit to wear the shirt” were directed at United’s players, while Pogba was singled by fans after another lacklustre performance in midfield.
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The France international was substituted during the second half to cheers from the home support, which turned to boos as he left the pitch.
A section of supporters then chanted "f*** off Pogba" at the midfielder, who is expected to leave United when his contract expires at the end of the season.
At the end of the match, Pogba was again booed as headed towards the tunnel.
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He then appeared to cup his ear in the direction of the United fans in a show of defiance.
When questioned about the chants after the match, United interim manager Ralf Rangnick said: "I didn't hear, but I was told after the game.
"I can totally understand the fans being frustrated, but I don't think they should be targeting players individually. This is not right or fair."
Victory for United sees them gain ground in the race for the top four after Tottenham and Arsenal were both beaten on Saturday.
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Spurs lost 1-0 at home to Brighton, while Arsenal were beaten 1-0 away at Southampton.
United are now just three points off the Champions League places and next face bitter rivals Liverpool away from home on Tuesday.
Goalkeeper David De Gea says the Red Devils must improve if they are to take anything away from Anfield.
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"We know we are not at our best moment. The most important thing is the victory and we are closer to the top four," De Gea told the BBC after full-time.
"The spirit is there. Everyone is dropping points ups and won so we have a chance. It's not enough to be in the top four. We should control the game from the beginning and not give them chances. We give chances to every team so we have to improve a lot.
"We take the three points and let's see on Tuesday [away to Liverpool]. I hope this victory gives us more confidence. We want to go there and try and win."
Topics: Paul Pogba, Manchester United, Football, Premier League, Norwich City