Jack Grealish is out of Manchester City's clash with Newcastle at St. James' Park with injury.
The England international came off the bench in City's 4-0 triumph over Bournemouth last weekend as Ilkay Gundogan, Kevin De Bruyne and Phil Foden were all amongst the goals.
Pep Guardiola's men take on Newcastle in their next league game before jetting off to Spain to prepare for a charity friendly with Barcelona next week.
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Kalvin Phillips and Cole Palmer have both made the bench for the Premier League champions on Saturday afternoon.
Ruben Dias is a surprise name amongst the substitutes, with John Stones partnering Nathan Ake in central defence.
Manchester City fans will also be pleased to see Bernardo Silva make his first league start of the season after only coming off the bench against West Ham and Bournemouth.
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However, after featuring in City's opening league games, Jack Grealish is missing from the matchday squad against Eddie Howe's men.
The 26-year-old suffered a knock against Bournemouth and is out with injury, with Bernardo Silva and Phil Foden lining up alongside Erling Haaland in attack.
Speaking to Sky Sports ahead of kick-off, Pep Guardiola said: "He (Grealish) had an incredible blow in the last game against Bournemouth in the last minutes.
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"We're lucky it was just a little, little, little damage to his ligament, but not much. He feels better, but not ready for today."
Grealish impressed on City's pre-season tour of the United States, starring in his side's 2-1 win over Club America.
The former Aston Villa skipper also set up Erling Haaland on his first appearance in Manchester City colours as the Blues picked up a 1-0 win over Bayern Munich.
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Guardiola rewarded Grealish for his performances in pre-season by starting him against West Ham on the opening day of the season.
Haaland netted twice on his Premier League debut as the English champions made a stellar beginning to their title defence.
It remains to be seen whether Grealish can recover in time to be involved against Barcelona next week.
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The Birmingham-born attacker joined City in a British-record move last summer and has taken time to adjust to life at the Etihad Stadium.
After making an encouraging start to his second campaign in Manchester, Grealish will be keen on kicking on from his first league winning season and racking up better attacking numbers.
Topics: Manchester City, Premier League, Jack Grealish, Pep Guardiola, Eddie Howe, Newcastle United, Bernardo Silva, Ilkay Gundogan, Kevin De Bruyne