Pep Guardiola has confirmed that Kyle Walker will miss Wednesday’s clash with FC Copenhagen.
The Premier League champions claimed bragging rights with an emphatic 6-3 thrashing of local rivals Manchester United at the Etihad Stadium on Sunday.
Boyhood blues Erling Haaland and Phil Foden netted a treble each in a scintillating attacking showing that saw Guardiola's men enter half time four goals to the good.
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City remain unbeaten across all competitions this season and sit in second place in the Premier League table - behind leaders Arsenal.
A perfect start to their Champions League campaign has put the 2021's finalists at the summit of their group, following wins over Sevilla and Borussia Dortmund in their opening games.
A brace from Haaland and strikes from Foden and Ruben Dias sealed a convincing victory at the Ramón Sánchez Pizjuán Stadium for the English champions on matchday one.
Guardiola's side were given a run for their money by Borussia Dortmund at the Etihad Stadium after a cagey first half that finished goalless.
Jude Bellingham gave the visitors the lead with a clever header following a corner before John Stones levelled proceedings with a long-range effort.
Erling Haaland did the inevitable and made the difference for Manchester City with an acrobatic finish from Joao Cancelo's cross into the six yard area.
Rodri suffered a calf injury in training ahead of City's derby win at the weekend, raising doubts over the Spain international's fitness for midweek.
Speaking ahead of the game on Wednesday evening, Pep Guardiola has provided an update on his squad's fitness in his press conference.
The Catalan has confirmed that Kyle Walker is out and that the Blues will have to wait and see on Rodri.
"We will train this afternoon and know if Rodri is better. Kyle is out. We will see the training session," said the City boss.
Walker suffered another injury setback on Sunday, with the Englishman forced off against United midway through the first-half.
Kalvin Phillips and John Stones both remain sidelined, although Guardiola revealed that he hopes Phillips can feature for City before the World Cup.
Phillips underwent shoulder surgery during the international break on a recurring problem.
The former Leeds midfielder joined City in a £42 million transfer this summer.
Topics: Manchester City, Pep Guardiola, Rodri, Kyle Walker, Kalvin Phillips, John Stones
Vayam Lahoti