Orel Grinfeld will lead a predominantly Israeli team of Match Officials when Manchester City host Sevilla on Wednesday.
The Sky Blues, who have already secured qualification and top spot in Group G, conclude their Group Stage campaign in midweek.
Manchester City are currently unbeaten in Europe this season, with successive goalless draws against FC Copenhagen and Borussia Dortmund ensuring first place for Pep Guardiola's side.
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Erling Haaland scored twice during the Blues' trip to Seville in Matchday One, with the Spanish side suffering a 4-0 loss to the Premier League Champions.
Phil Foden and Ruben Dias were also on the scoresheet during September's victory.
Ahead of Wednesday's meeting at the Etihad Stadium, UEFA have announced the Match Officials for the Matchday Six clash.
Match Referee
Orel Grinfeld will lead a predominantly Israeli team of Match Officials at the Etihad Stadium in midweek.
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The 41 year-old has taken charge of three Champions League fixtures so far this season, showing 11 yellow cards and one red card.
Grinfeld last refereed City in 2019, when Phil Foden was sent off during a 5-1 thrashing of Atalanta.
The Israeli referee officiated in England in March, when Leicester beat Rennes in the Europa Conference League.
Manchester City's Phil Foden is sent off by referee Orel Grinfeld (Image: PA Images/Alamy)
Assistant Referees
Grinfeld will be accompanied in East Manchester by Assistant Referees Roy Hassan and Idan Yarkoni.
Video Assistant Referees
Overviewing proceedings will be Roi Reinshreiber, who has been named as the Video Assistant Referee.
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Reinshreiber will be alongside Assistant Video Assistant Referee Paolo Valeri for Wednesday's match.
Fourth Official
Gal Leibovitz has been named as the Fourth Official for the match.
The referee will be overseeing conduct within the two dugouts, and the behaviour of managers Pep Guardiola and Jorge Sampaoli.
Topics: Manchester City, Sevilla, Champions League, Pep Guardiola